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The only thing that really matters is Corporate Profit. This drug price is very high at around $1000. I suppose Bayer needs to collect as much cash as they can before the patient dies. It would be nice to have a Medical and a Sad channel. Comments  playlists with this video "what's d problem?" To expect the awful by marinara
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I have tremendous respect for Dr. Mangano. He has done some REALLY important work. However, it's important to carefully listen to what he said about the drug. He said about his study, "it's shown a TREND towards increased risk of death in-hospital." Medical researchers use the word "trend" to indicate the association between the drug and increased risk of death did not reach a p = .05, which is the standard measure of causation in medical literature. A probability ratio of .05 simply means there is a 5% probability that what you observe is occurring by chance alone.
The FDA mirrors this statement regarding the association not reaching a level of "statistical significance."
http://www.fda.gov/Cder/drug/early_comm/aprotinin.htm
However, I don't know the probability number they did come up with, and evidently it was close enough to .05 that they began to assume causation.
What the studies did confirm was that aprotinin was effective at reducing blood loss during heart surgery, and it was associated with less blood transfusion. If you look at that on the surface, it sounds good because bleeding and transfusion is a significant cause of surgical morbidity and death.
The title of this video includes "Trasydol kills thousands" The commentator clearly states, "Trasydol MAY HAVE CONTRIBUTED to the deaths of thousands of patients." So, the title bends a possibility to a proof. Further, in the majority of cases, it is nearly impossible to say the drug was the ACTUAL cause of the complication in any given case. Was the surgeon who operated on this man trying to deflect blame away from shoddy surgical technique. Believe me, physicians are all too quick to point the finger at someone else.
And, no open heart surgery is routine. It averages around 1 death per hundred cases, hardly routine.
All that being said, I'm not going to defend BAYER. It sounds as if they acted in an irresponsible manner. These days it often appears drug companies wait too long when a "trend" is developing. It seems they are content to wait until they hear the studies have shown a p value of .05. Profits over probabilities. It's a disgrace.